除草菌素A对支原体、无胆甾原体、脲原体和螺原体属的活性。
Activity of herbicolin A against Mycoplasma, Acholeplasma, Ureaplasma, and Spiroplasma species.
作者信息
Freundt E A, Winkelmann G
出版信息
Antimicrob Agents Chemother. 1984 Jul;26(1):112-4. doi: 10.1128/AAC.26.1.112.
Abstract
Herbicolin A, a novel acyl peptide antibiotic, inhibits the growth of the sterol-requiring Mycoplasma, Ureaplasma, and Spiroplasma species, with MICs varying from 1.5 to 100 micrograms/ml. With the exception of Acholeplasma modicum, all of the non-sterol-requiring species of the family Acholeplasmataceae were totally resistant to herbicolin A when tested on serum-containing medium but were inhibited to some extent on medium devoid of serum and any other source of sterol or fatty acids.
摘要
除草菌素A是一种新型酰基肽抗生素，可抑制需要固醇的支原体、脲原体和螺旋原体属细菌的生长，其最低抑菌浓度（MIC）在1.5至100微克/毫升之间。除了少量无胆甾原体之外，在含血清培养基上进行测试时，无胆甾原体科所有不需要固醇的菌种对除草菌素A均完全耐药，但在不含血清以及任何其他固醇或脂肪酸来源的培养基上会受到一定程度的抑制。
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