生理分娩中产妇血清、新生儿脐血及羊水中G、A和M免疫球蛋白水平。

G, A and M immunoglobulin levels in parturient's blood serum, umbilical blood of their neonates and the amniotic fluid in physiological deliveries.

作者信息

Gryboś M

出版信息

Arch Immunol Ther Exp (Warsz). 1984;32(1):127-34.

Abstract

The present investigation is aimed at determination of G, A and M immunoglobulins concentration levels in the blood serum of parturients, umbilical blood of their neonates and in the amniotic fluid in 50 women with physiological pregnancy and delivery whose neonates were fully mature. In order to evaluate IgG, IgA and IgM concentration in the biological fluids, the method of inhibition of passive hemagglutination was applied. IgG and IgA were detected in all the three environments, while the presence of IgM was confirmed in all cases in the blood serum but only in 78% of the tested samples of the aminotic fluid. Mean values of IgG and IgM concentration both in the parturients' serum as well as in the umbilical blood of their neonates as compared with the values found in the amniotic fluid, revealed statistically significant differences. The statistically significant correlation noted between the values of IgG concentration in the parturients' serum and the umbilical blood of their neonates was not confirmed in the case of IgA and IgM.

摘要

本研究旨在测定50例足月妊娠且分娩的产妇血清、新生儿脐血及羊水样本中G、A和M免疫球蛋白的浓度水平。为评估生物样本中IgG、IgA和IgM的浓度，采用被动血凝抑制法。在所有三种样本中均检测到IgG和IgA，血清样本中均检测到IgM，而羊水样本中仅78%的检测样本检测到IgM。与羊水样本相比，产妇血清和新生儿脐血中IgG和IgM的平均浓度有统计学显著差异。产妇血清和新生儿脐血中IgG浓度值之间具有统计学显著相关性，但IgA和IgM则未证实此相关性。