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[Oxygen balance and the effect of antihypoxic preparations in fluorine poisoning].

作者信息

Shugaev V A

出版信息

Farmakol Toksikol. 1984 Jul-Aug;47(4):94-7.

PMID:6479320
Abstract

Long-term inhalations of fluoride at concentrations of 0.58 and 2.75 mg/m3 distrub oxygen regimen in experimental animals (O2 consumption, tension and utilization in the muscle, tissue respiration). During fluorine intoxication, some of the antihypoxic agents (NAD X H, adenine nucleotides, guthimin, bemitil, apressin and glutamic acid) exert a beneficial therapeutic effect. Administration of the glycolysis substrates, NAD, NADP, cytochrome c and sodium hydroxybutyrate, did not exert any marked therapeutic action.

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