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[不同种类海洋膏剂对氟中毒大鼠肝脏生化指标的影响]

[Effect of different kinds of Ocean paste on rat liver biochemical indices in sodium fluoride poisoning].

作者信息

Maĭstruk P N, Pliss M B, Levinton Zh B, Gorban' G P, Grigor'eva N N

出版信息

Vopr Pitan. 1981 May-Jun(3):48-51.

PMID:7269448
Abstract

The paper is concerned with the effect of diets including three chemically different types of the "Ocean" paste on biochemical characteristics (glycolysis, the content of phosphofructokinase, dehydrogenase, glucoso-6- phosphate, demethylase, dimethylalaniline hydroxylase, ascorbic acid) of the liver of rats exposed to sodium fluoride overdosage. The test diets were compared with those containing conventional sources of protein (casein, beef). Acute exposure to sodium fluoride caused changes in the biochemical characteristics. The most appreciable changes were seen in the group of rats fed beef. As compared with control, the shifts in the biochemical characteristics were negligible provided the rats exposed to acute and chronic poisoning received the diet supplemented with the paste. No morphological changes were found in the internal organs. The data obtained indicate that the type C "Ocean" paste has a protective action in sodium fluoride poisoning.

摘要

本文关注含三种化学性质不同的“海洋”糊剂的日粮对过量摄入氟化钠的大鼠肝脏生化特性(糖酵解、磷酸果糖激酶、脱氢酶、葡萄糖-6-磷酸、脱甲基酶、二甲基苯胺羟化酶、抗坏血酸含量)的影响。将受试日粮与含传统蛋白质来源(酪蛋白、牛肉)的日粮进行比较。急性暴露于氟化钠会导致生化特性发生变化。在喂食牛肉的大鼠组中观察到最明显的变化。与对照组相比,急性和慢性中毒的大鼠摄入添加了糊剂的日粮后,生化特性的变化可忽略不计。在内脏器官中未发现形态学变化。所获得的数据表明,C型“海洋”糊剂对氟化钠中毒具有保护作用。

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