Hoogewijs G, Massart D L
J Chromatogr. 1984 Aug 10;309(2):329-37. doi: 10.1016/0378-4347(84)80040-7.
Assay methods for measuring saliva levels of carbamazepine and its active metabolite, and of amidopyrine are developed using a standardized analysis strategy. Both assay methods include ion-pair extraction of the analytes with octylsulphate as the counter-ion and chromatography on a CN-bonded phase using a hexane--dichloromethane--acetonitrile--propylamine mixture as the mobile phase. Both methods are applied to patient samples.
采用标准化分析策略开发了测量卡马西平及其活性代谢物以及氨基比林唾液水平的检测方法。两种检测方法均包括以辛基硫酸盐为反离子对分析物进行离子对萃取，并使用己烷 - 二氯甲烷 - 乙腈 - 丙胺混合物作为流动相在氰基键合相上进行色谱分析。两种方法均应用于患者样本。
