Imamura S, Yamada M, Yamamoto K
J Am Acad Dermatol. 1984 Aug;11(2 Pt 1):203-9. doi: 10.1016/s0190-9622(84)70150-2.
To determine the course and prognosis and also to reexamine the clinical and histologic features of lipodystrophia centrifugalis abdominalis infantilis, originally described by Imamura et al in 1971, a questionnaire was sent to 94 dermatology and pediatric departments in Japan. Data on 86 cases collected from 44 departments confirmed the unique and distinct features of this disease: onset by age 3, development of the lesion in the groin, axillae, or their surroundings, presence of slightly inflammatory areas around the depressed one, and histologically, loss of subcutaneous fat in the depressed area with panniculitis in the surrounding area. The depressed lesions were found to enlarge centrifugally for several years and to involve a large part of the abdominal and/or chest wall. However, the enlargement was found to stop spontaneously by age 13, and the depressed area tended to undergo recovery thereafter.
为了确定婴儿腹部离心性脂肪营养不良的病程和预后，并重新审视其临床和组织学特征（该病最初由今村等人于1971年描述），我们向日本94个皮肤科和儿科科室发送了一份调查问卷。从44个科室收集到的86例病例数据证实了该病的独特特征：3岁前发病，病变发生在腹股沟、腋窝或其周围，凹陷部位周围存在轻度炎症区域，组织学上，凹陷区域皮下脂肪缺失，周围区域有脂膜炎。发现凹陷性病变会离心性扩大数年，并累及腹部和/或胸壁的大部分区域。然而，发现这种扩大在13岁时会自发停止，此后凹陷区域倾向于恢复。
