Bell R R, McGill T J, Digby P W, Bennett S A
J Nutr. 1984 Oct;114(10):1900-8. doi: 10.1093/jn/114.10.1900.
The effects of exercise and of dietary protein level on energy metabolism and brown adipose tissue (BAT) activity were investigated in weaning male mice. Mice were fed diets providing low (7.5%), adequate (12.5%) or high (25%) levels of dietary protein. Half of the animals in each dietary group were given moderate exercise by swimming. The lower the level of dietary protein, the greater the increase in food intake, energy expenditure, body fat and BAT mass; however, total-carcass energy, food efficiency and BAT activity were not affected by the level of dietary protein. In experiment 2, BAT was compared in mice swimming at 33 degrees C and 36 degrees C with non-exercised controls. In a third experiment, energy balance and BAT activity were compared in rats exercised at 36 degrees C and in paired weight gain (PWG) rats whose food intake was restricted to achieve weight gains equal to that of the exercised rats. PWG rats maintained carcass energy content equal to that of the controls and significantly greater than the exercised rats by decreasing energy expenditure. Moderate exercise did not affect food intake, whereas rigorous exercise decreased energy intake. Exercise did not affect BAT mass or thermogenic activity; however, mild cold stress did increase BAT activity. Exercise decreased body fat, carcass energy and food efficiency without affecting BAT.
研究了运动和膳食蛋白质水平对断奶雄性小鼠能量代谢及棕色脂肪组织（BAT）活性的影响。给小鼠喂食蛋白质水平低（7.5%）、适中（12.5%）或高（25%）的膳食。每个膳食组中有一半的动物通过游泳进行适度运动。膳食蛋白质水平越低，食物摄入量、能量消耗、体脂和BAT质量的增加就越大；然而，胴体总能量、食物效率和BAT活性不受膳食蛋白质水平的影响。在实验2中，将在33摄氏度和36摄氏度游泳的小鼠的BAT与未运动的对照小鼠进行比较。在第三个实验中，将在36摄氏度运动的大鼠与成对体重增加（PWG）大鼠的能量平衡和BAT活性进行比较，PWG大鼠的食物摄入量受到限制，以使其体重增加量与运动大鼠相等。PWG大鼠通过减少能量消耗，使胴体能量含量与对照大鼠相等，且显著高于运动大鼠。适度运动不影响食物摄入量，而剧烈运动则会减少能量摄入。运动不影响BAT质量或产热活性；然而，轻度冷应激确实会增加BAT活性。运动可减少体脂、胴体能量和食物效率，而不影响BAT。
