Welling R E, Cranley J J, Krause R J, Hafner C D, Arbaugh J J, Roedersheimer L R
J Vasc Surg. 1984 Jan;1(1):57-61. doi: 10.1067/mva.1984.avs0010057.
From January 1980 until May 1983, 24 patients had surgical exploration of the carotid bifurcation for suspected recent total occlusion of the internal carotid artery (ICA). All patients had recent onset of neurologic symptoms related to the ipsilateral cerebral hemisphere. Selective carotid angiography determined preoperative total occlusion of the ICA. Because surgery failed to reopen the ICA in nine patients, they had endarterectomy of the external carotid artery. Fifteen patients had initially successful thromboendarterectomy of the ICA. Prior to patient dismissal, patency was documented by B-mode ultrasound or digital subtraction angiography (DSA). All 15 patients had another B-mode ultrasound scan or DSA at least 45 days after thromboendarterectomy. On reexamination four ICAs were reoccluded, but only one patient became symptomatic. There were no operative deaths and no increase in preoperative neurologic deficits. The natural history of patients with total occlusion of the ICA is variable. The most important factor influencing a therapeutic decision is the patient's neurologic status. This study supports an aggressive, early surgical intervention for recent total occlusion in carefully selected patients.
从1980年1月至1983年5月,24例患者因怀疑颈内动脉(ICA)近期完全闭塞而接受了颈动脉分叉处的手术探查。所有患者近期均出现与同侧脑半球相关的神经症状。选择性颈动脉血管造影确定术前ICA完全闭塞。由于9例患者手术未能使ICA再通,故对其进行了颈外动脉内膜切除术。15例患者最初成功进行了ICA血栓内膜切除术。在患者出院前,通过B型超声或数字减影血管造影(DSA)记录血管通畅情况。所有15例患者在血栓内膜切除术后至少45天进行了另一次B型超声扫描或DSA检查。复查时发现4条ICA再次闭塞,但只有1例患者出现症状。无手术死亡病例,术前神经功能缺损也未增加。ICA完全闭塞患者的自然病程各不相同。影响治疗决策的最重要因素是患者的神经状态。本研究支持对精心挑选的近期完全闭塞患者进行积极的早期手术干预。