Jagger J, Fife D, Vernberg K, Jane J A
Neurosurgery. 1984 Sep;15(3):303-6. doi: 10.1227/00006123-198409000-00002.
Because alcohol intoxication is common among brain-injured patients, we performed this study to determine the extent to which alcohol alters the initial assessment of brain injury severity in these patients by depressing the level of consciousness. The Glasgow coma scale was used to measure the level of consciousness of 257 brain-injured adults admitted to the University of Virginia Hospital, both on arrival in the emergency room and 6 to 10 hours later. Improvement in the level of consciousness between the first and second measurements was significantly related to the blood alcohol concentration on admission. Patients with the highest blood alcohol concentrations showed the greatest improvement. Most of this effect occurred in patients with a blood alcohol concentration of 0.20% or higher. Alcohol intoxication is a potential source of bias in the clinical classification of brain injuries according to severity.
由于酒精中毒在脑损伤患者中很常见，我们进行了这项研究，以确定酒精通过降低意识水平改变这些患者脑损伤严重程度初始评估的程度。使用格拉斯哥昏迷量表来测量弗吉尼亚大学医院收治的257名成年脑损伤患者在抵达急诊室时以及6至10小时后的意识水平。首次和第二次测量之间意识水平的改善与入院时的血液酒精浓度显著相关。血液酒精浓度最高的患者改善最为明显。这种影响大多发生在血液酒精浓度为0.20%或更高的患者中。酒精中毒是根据严重程度对脑损伤进行临床分类时潜在的偏差来源。
