Pulido J S, Palacio M, Peyman G A, Fiscella R, Greenberg D, Stelmack T
Ophthalmic Surg. 1984 Aug;15(8):666-9.
Two systemic agents, vidarabine and acyclovir, were tested for ocular toxicity in intravitreal injection and vitrectomy infusion solutions. On the basis of this study we recommend using up to 30 mcg/0.1 ml of vidarabine as an intraocular injection or 8 to 16 mcg/ml in vitrectomy infusion fluid. For acyclovir, 80 mcg/0.1 ml as an intraocular injection or 40 mcg/ml in vitrectomy infusion fluid may be a therapeutic adjunct for managing viral retinitis.
对两种全身用药阿糖腺苷和阿昔洛韦进行了玻璃体内注射和玻璃体切割术输液溶液的眼毒性测试。基于本研究，我们建议玻璃体内注射阿糖腺苷的剂量最高为30 mcg/0.1 ml，或玻璃体切割术输液液中为8至16 mcg/ml。对于阿昔洛韦，玻璃体内注射80 mcg/0.1 ml或玻璃体切割术输液液中40 mcg/ml可能是治疗病毒性视网膜炎的辅助治疗方法。
