Hesch R D
Dtsch Med Wochenschr. 1978 May 12;103(19):811-5. doi: 10.1055/s-0028-1104516.
Questionnaires were sent to 23 centres in ten countries. Results indicate that, for ethical, scientific, clinical and socio-economic reasons, screening for neonatal hypothyroidism should be undertaken. Pilot studies are no longer required. Distribution of the birth-rate in the various lands of the German Federal Republic suggest that, assuming appropriate technical and staffing provision, ten centres with a sample rate of 200/day would be sufficient for full screening. Because of special features in quality control of radioimmunochemical methods, a uniform manner of setting up the necessary laboratories is essential.
调查问卷被发送到十个国家的23个中心。结果表明，出于伦理、科学、临床和社会经济原因，应开展新生儿甲状腺功能减退症筛查。不再需要进行试点研究。德意志联邦共和国不同地区的出生率分布表明，假设提供适当的技术和人员配备，十个样本率为每天200例的中心就足以进行全面筛查。由于放射免疫化学方法质量控制的特殊特点，以统一方式建立必要的实验室至关重要。
