Evert W, Grüttner R
Z Geburtshilfe Perinatol. 1980 Jun;184(3):180-6.
Summing up, we can say that, basing on the hypothyreosis screening results obtained in the Federal Republic of Germany, a rate of 100 to 160 new hypothyreosis patients must be expected annually for every 500.000 births. Of these more than half is recognized at a time only at which irreparable damage of the central nervous system has already occurred. With the help of TSH screening, a large proportion of these patients can be saved from several mental retardation and damage, with all its severe social consequences, by enabling early institution of appropriate therapeutics measures. Hence, it would be desirable to achieve, throughout the territory of the Federal Republic, comprehensive hypothyreosis screening in combination with already introduced programme of screening in respect of metabolism, covering without exceptions all newborn and comprising responsible, rapid and efficient co-operation without "red tape", between obstetricians or midwives on the one hand and screening centers on the other.
综上所述,基于在德意志联邦共和国获得的甲状腺功能减退症筛查结果,每50万例出生中,预计每年会有100至160例新的甲状腺功能减退症患者。其中一半以上患者是在中枢神经系统已遭受不可修复损害时才被确诊。借助促甲状腺激素筛查,通过早期实施适当的治疗措施,很大一部分这类患者可避免智力迟钝及损害及其所有严重的社会后果。因此,在德意志联邦共和国全境,理想的做法是将全面的甲状腺功能减退症筛查与已推行的代谢筛查计划相结合,无一例外地涵盖所有新生儿,且产科医生或助产士与筛查中心之间要进行负责、迅速且高效的合作,避免“繁琐手续”。