Domingo J L, Llobet J M
Rev Esp Fisiol. 1984 Jun;40(2):231-6.
A study in rats was made of the effects produced by L-cysteine on the acute toxicity of cobalt chloride given orally and intraperitoneally. The decrease in lethality was absolute for the different doses tested, except when the CoCl2 was given orally and L-cysteine intraperitoneally in which only 40% efficiency was obtained. No specially significant changes were observed in the blood parameters of the animals treated with the CoCl2-cysteine complex after one week. Significant differences were noted between serum parameters: glucose, triglycerides and cholesterol, measured in rats after twelve hours of receiving the CoCl2-cysteine complex, compared with the same parameters measured when the CoCl2 was given without complex.
对大鼠进行了一项研究，以探究L-半胱氨酸对口服和腹腔注射氯化钴急性毒性产生的影响。除了口服CoCl2并腹腔注射L-半胱氨酸的情况（此时仅获得40%的效率）外，对于所测试的不同剂量，致死率的降低是绝对的。用CoCl2-半胱氨酸复合物处理的动物在一周后，其血液参数未观察到特别显著的变化。在接受CoCl2-半胱氨酸复合物12小时后的大鼠中测量的血清参数（葡萄糖、甘油三酯和胆固醇）与未复合给予CoCl2时测量的相同参数之间存在显著差异。
