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感染 HBs 阳性病毒性肝炎的血吸虫病患者体内乙肝抗原的表现

Behaviour of hepatitis B antigen in bilharzial patients infected with HBs positive viral hepatitis.

作者信息

Nooman M Z, Khalil M, Nafeh M, Elwan S I, el-Sharkawi M, Omar A M, Atta S M, Reda I

出版信息

Egypt J Bilharz. 1978;4(1):79-87.

PMID:648458
Abstract

A TOTAL of 204 cases with acute viral hepatitis were studied: 93 bilharzial and 111 non-bilharzial. This study is concerned with the 106 cases showing positive HBS Ag test. Follow up of the cases after discharge from the Fever Hospital was carried out by repeated clinical and laboratory examinations 3 montly in the first year and 6 monthly subsequently. The bilharzial and non-bilharzial patients were found to be equally susceptible to HBS Ag positive hepatitis (p=0.25). However, antigenaemia tended to last longer as a whole in the bilharzial patients (p=0. 005) and was not affected by successful specific antibilharzial treatment. It seems that bilharzial infection predisposes to "retention" of HBs antigen, after subsidance of the acute attack, thus increasing the volume of reservoir for HB virus in our rural community.

摘要

共研究了204例急性病毒性肝炎患者:93例为血吸虫性,111例为非血吸虫性。本研究关注的是106例乙肝表面抗原(HBS Ag)检测呈阳性的病例。对这些病例从发热医院出院后进行随访,在第一年每3个月进行一次重复临床和实验室检查,之后每6个月检查一次。发现血吸虫性和非血吸虫性患者对乙肝表面抗原阳性肝炎的易感性相同(p = 0.25)。然而,总体而言,血吸虫性患者的抗原血症持续时间更长(p = 0.005),且不受成功的特异性抗血吸虫治疗的影响。似乎血吸虫感染使急性发作消退后乙肝表面抗原易于“留存”,从而增加了我们农村社区乙肝病毒的储存量。

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Behaviour of hepatitis B antigen in bilharzial patients infected with HBs positive viral hepatitis.感染 HBs 阳性病毒性肝炎的血吸虫病患者体内乙肝抗原的表现
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