Hartmann H, Fischer G, Janning G
Z Gastroenterol. 1984 Jul;22(7):343-5.
A case of prolonged cholestatic jaundice and leukopenia occurring in a 60 year old wh piroxicam--a non-steroidal antiinflammatory agent--is reported. Histological examination of liver biopsy revealed pronounced canalicular and intracellular bile retention. After discontinuation of the drug serum bilirubin declined to normal values over a period of 10 weeks.
报告了一例60岁患者出现长期胆汁淤积性黄疸和白细胞减少症的病例，该患者服用了非甾体抗炎药吡罗昔康。肝脏活检的组织学检查显示明显的胆小管和细胞内胆汁潴留。停药后，血清胆红素在10周内降至正常水平。
