Muller-Fassbender H H, Nagel E
Eur J Rheumatol Inflamm. 1983;6(1):106-12.
Indomethacin retard and piroxicam were compared in an open, randomized, parallel study in the treatment of osteoarthritis. Improvement of the symptoms of the disease was highly significant for both drugs. There was no statistical difference between the two drugs in terms of efficacy. Number and duration of side effects were significantly lower with piroxicam than with indomethacin retard. Piroxicam was administered once a day. Indomethacin retard was always (43% of the cases) or sometimes (14%) given twice daily.
在一项治疗骨关节炎的开放性、随机、平行研究中,对缓释吲哚美辛和吡罗昔康进行了比较。两种药物对疾病症状的改善都非常显著。两种药物在疗效方面没有统计学差异。吡罗昔康的副作用数量和持续时间明显低于缓释吲哚美辛。吡罗昔康每日给药一次。缓释吲哚美辛总是(43%的病例)或有时(14%)每日给药两次。