Okamura K, Ito K, Suzuki Y, Shimoji T
Hinyokika Kiyo. 1984 Apr;30(4):459-65.
Twenty-seven cases in which cancer could not be distinguished from chronic cystitis were reviewed. These cases were divided into those with and those without a past history of bladder tumor. The high frequency of hyperplasia in the group with a history of bladder tumor suggested that hyperplasia may be a precursor of papillary tumor. On the other hand, proliferative lesions such as cystitis cystica and metaplasia were encountered in the group with no history of bladder tumor and 50 percent had symptoms of chronic cystitis. These findings suggested that proliferative lesions in the bladder developed by inflammatory irritation. Urinary cytology was done in 18 cases. Cytology was positive in 2 of the 3 cases of transitional cell carcinoma. Therefore, urinary cytology was useful, but it did not provide distinction in two cases of follicular cystitis and a case of squamous metaplasia was false positive.
回顾了27例无法将癌症与慢性膀胱炎区分开来的病例。这些病例被分为有膀胱肿瘤既往史和无膀胱肿瘤既往史两组。有膀胱肿瘤病史的组中增生的高频率表明增生可能是乳头状肿瘤的前驱病变。另一方面，在无膀胱肿瘤病史的组中遇到了诸如囊性膀胱炎和化生等增殖性病变，且50%的患者有慢性膀胱炎症状。这些发现表明膀胱中的增殖性病变是由炎性刺激发展而来的。对18例患者进行了尿液细胞学检查。3例移行细胞癌中有2例细胞学检查呈阳性。因此，尿液细胞学检查是有用的，但在2例滤泡性膀胱炎中无法区分，且1例鳞状化生病例出现假阳性。
