[New data on the mechanism of organic substance secretion by the kidney].

The substrate stimulation of renal secretory transport of cardiotrast and penicillin have been studied in conscious rats. This phenomenon takes place not only after repeated injections of substrates three times daily during three days but also after administration of the compounds for two or one days or twice daily with interval of two hours. The tubular secretion of organic substances seems to be the substrate inducing process.