Awunor-Renner C, Lawande R, Subbuswamy S G
Ann Trop Med Parasitol. 1984 Jun;78(3):287-93. doi: 10.1080/00034983.1984.11811818.
In a consecutive series of 134 adult patients with glomerular disease, 82.7% showed proliferative glomerulonephritis on renal biopsy; 45% of the cases were asymptomatic. Nephrotic syndrome in adults in northern Nigeria should respond to immunosuppressive therapy only rarely. There was no evidence to implicate Plasmodium malariae as the cause of glomerular disease in adults in the savannah belt in Nigeria. The roles of hepatitis B virus and Yersinia enterocolitica were discussed and require further serological investigations. O-serotype 8 yersiniosis is reported outside the USA for the first time and is possibly nephritogenic. Hepatosplenomegalic schistosomiasis is also reported for the first time in Africa south of the Sahara. The role of the eradication of infections due to the Streptococcus, hepatitis B virus, P. malariae, schistosomes and Y. enterocolitica in the reduction of glomerular disease is discussed.
在连续的134例成年肾小球疾病患者中，82.7%的患者肾活检显示为增殖性肾小球肾炎；45%的病例无症状。尼日利亚北部成年患者的肾病综合征很少对免疫抑制治疗有反应。没有证据表明间日疟原虫是尼日利亚萨凡纳地区成年患者肾小球疾病的病因。讨论了乙型肝炎病毒和小肠结肠炎耶尔森菌的作用，需要进一步进行血清学调查。首次在美国以外地区报告了O血清型8型耶尔森菌病，它可能具有致肾炎性。在撒哈拉以南非洲地区也首次报告了肝脾肿大性血吸虫病。讨论了根除链球菌、乙型肝炎病毒、间日疟原虫、血吸虫和小肠结肠炎耶尔森菌感染在减少肾小球疾病方面的作用。
