Zaki K, el Hak R, Amer W, Saleh F, El Faras A, Ragab L, Nour H
Biomed Biochim Acta. 1984;43(6):749-54.
Salivary estradiol 17 beta (E2-17 beta) and progesterone (P) were determined by using radioimmunoassay techniques in 30 pregnant females in the first, second and third trimesters as well as in 10 non-pregnant controls during the luteal phase of the menstrual cycle. Plaque index (P.I.), gingival index (G.I.) and retention index (R.I.) were measured in all cases. The data obtained showed that the levels of the two hormones in saliva were significantly increasing during the 3 trimesters of pregnancy. P.I. and R.I. did not change, however, G.I. was significantly higher in the second and third trimesters when compared with controls. A correlation between both E2--17 beta and P during pregnancy and gingival changes is suggested.
采用放射免疫分析技术测定了30例处于妊娠早、中、晚期的孕妇以及10例处于月经周期黄体期的非孕对照者唾液中17β-雌二醇（E2-17β）和孕酮（P）的含量。对所有研究对象均测量了菌斑指数（P.I.）、牙龈指数（G.I.）和滞留指数（R.I.）。所得数据显示，在妊娠的3个阶段，唾液中这两种激素的水平均显著升高。然而，P.I.和R.I.未发生变化，与对照组相比，G.I.在妊娠中晚期显著升高。提示妊娠期间E2-17β和P与牙龈变化之间存在相关性。
