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Reactions of the aminoacyl-tRNA synthetase-aminoacyl adenylate complex and amino acid derivatives. A new approach to peptide synthesis.

作者信息

Nakajima H, Kitabatake S, Tsurutani R, Tomioka I, Yamamoto K, Imahori K

出版信息

Biochim Biophys Acta. 1984 Oct 23;790(2):197-9. doi: 10.1016/0167-4838(84)90224-3.

Abstract

Several kinds of dipeptide derivative were shown to be formed by the reactions of the aminoacyl adenylate-aminoacyl-tRNA synthetase complex and amino acid ester or amide. It was shown that the peptide bond could be formed by aminoacyl-tRNA synthetases even in the absence of the ribosome.

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