Meryon S D
Biomaterials. 1984 Sep;5(5):293-7. doi: 10.1016/0142-9612(84)90076-0.
When freshly triturated, two zinc-containing amalgams, Velvalloy and Dispersalloy, were more cytotoxic in vitro than two zinc-free amalgams Amalcap and Sybraloy. The high copper amalgam, Sybraloy, was only slightly irritant: similarly the presence of copper in Dispersalloy did not increase its toxicity over Velvalloy. All four amalgams retained some degree of toxicity up to one month after setting which is in marked contrast to most other dental materials investigated previously. This was greatest with the zinc-containing amalgams and was accompanied by the continued release of zinc over this period.
刚研磨时，两种含锌汞合金Velvalloy和Dispersalloy在体外比两种无锌汞合金Amalcap和Sybraloy的细胞毒性更强。高铜汞合金Sybraloy仅有轻微刺激性：同样，Dispersalloy中铜的存在并未使其毒性比Velvalloy增加。所有四种汞合金在凝固后长达一个月的时间内都保留了一定程度的毒性，这与之前研究的大多数其他牙科材料形成了鲜明对比。含锌汞合金的这种情况最为明显，并且在此期间伴有锌的持续释放。
