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人体动脉可扩张模型中非牛顿流体的脉动流。

Pulsatile flow of non-Newtonian fluid in distensible models of human arteries.

作者信息

Liepsch D, Moravec S

出版信息

Biorheology. 1984;21(4):571-86. doi: 10.3233/bir-1984-21416.

Abstract

In addition to biochemical factors, hydromechanical influences are responsible for atherogenesis and deposits of blood platelets at bends and bifurcations of human arteries. Hence the flow patterns were simulated in a true-to-scale three-dimensional bifurcation of a human renal artery model and of an arterial femoralis with Newtonian and non-Newtonian blood like fluid. Investigations were made with steady and pulsatile flow. The velocity profiles (at physiological Re-numbers) were measured after the bifurcations with a laser-Doppler-anemometer. In previous works Newtonian fluids were used to investigate the flow in bends and bifurcations of rigid and elastic simplified models. In this paper, emphasis is placed on the difference between rigid and elastic models and also Newtonian and non Newtonian flow behavior. Differences between Newtonian and non Newtonian fluids may especially be expected to occur after branches where the flow has local strong convective elements such as in reverse zones and flow separation points.

摘要

除了生化因素外,流体力学影响也是动脉粥样硬化以及人体动脉弯曲和分叉处血小板沉积的原因。因此,在一个按比例缩小的真实三维人体肾动脉模型和股动脉模型的分叉处,分别使用牛顿流体和非牛顿类血液流体对血流模式进行了模拟。研究了稳定流和脉动流情况。在分叉后,使用激光多普勒风速仪测量了(在生理雷诺数下的)速度剖面。在之前的研究中,牛顿流体被用于研究刚性和弹性简化模型的弯曲和分叉处的流动。本文重点关注刚性模型和弹性模型之间的差异,以及牛顿流体和非牛顿流体的流动行为差异。牛顿流体和非牛顿流体之间的差异尤其可能出现在分支之后,在这些地方,流动具有局部强烈的对流元素,如在反向区域和流动分离点。

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