Delone G V, Tsirekidze N N, Brodskiĭ V Ia
Biull Eksp Biol Med. 1984 Sep;98(9):364-6.
Neonatal mice were grown until 3 weeks of age at a rate of four or sixteen per litter (groups I and II, respectively). The group I animals were characterized by accelerated growth. At day 21 of postnatal development their body and heart weights were three times greater than those of the group II animals. The mean protein content in cardiomyocytes of the group I animals increased faster, correlating with the increase of the heart weight. The fast-growing mice showed an increase in the number of polyploid cardiomyocytes (polynucleate cells mainly), amounting to 15-16% as compared with 2-4% seen in normal and slow-growing animals.
新生小鼠以每窝4只或16只的数量（分别为I组和II组）饲养至3周龄。I组动物的特点是生长加速。在出生后第21天，它们的体重和心脏重量是II组动物的三倍。I组动物心肌细胞中的平均蛋白质含量增加得更快，这与心脏重量的增加相关。快速生长的小鼠多倍体心肌细胞（主要是多核细胞）数量增加，占比达15 - 16%，而正常和生长缓慢的动物中这一比例为2 - 4%。
