Brodsky V Y, Delone G V, Tsirekidze N N
Cell Differ. 1985 Sep;17(3):175-81. doi: 10.1016/0045-6039(85)90485-3.
The number of myocytes and the percentage of cells with a high degree of ploidy increased in the heart ventricles of fast-growing mice compared with slow-growing ones. The mean incidence of octa- and hexadecaploid (by summary DNA content) myocytes was 7% in the slow-growing and 23% in the fast-growing, weaned mice. In these groups, the total myocyte number varied by 20%. There were 43% more myocyte genomes in the heart ventricles of the fast-growing mice than in those of the slow-growing mice. The same differences in cell number and ploidy persist in 90-day-old mice in spite of feeding ad libitum after weaning.
与生长缓慢的小鼠相比，生长快速的小鼠心室中的心肌细胞数量以及高度多倍体细胞的百分比增加。通过总结DNA含量，八倍体和十六倍体心肌细胞的平均发生率在生长缓慢的断奶小鼠中为7%，在生长快速的断奶小鼠中为23%。在这些组中，心肌细胞总数相差20%。生长快速的小鼠心室中的心肌细胞基因组比生长缓慢的小鼠多43%。尽管断奶后自由采食，但在90日龄小鼠中，细胞数量和多倍性方面的相同差异仍然存在。
