Aleksandrova T B, Rodionov I M, Shinkarenko V S
Biull Eksp Biol Med. 1984 Sep;98(9):366-8.
Brain stem microvessels up to 15 microns in diameter of spontaneously hypertensive rats and rats with experimental renal hypertension were investigated in histological sections with the aid of a texture analysis system. Hypertensive animals showed a reduction in the vascular diameter per unit volume of cerebral tissue, in the mean vascular diameter as well as in the area occupied by the vessels, thus attesting to the lessened density of brain vascularization. The proportion of the vessels measuring from 6 to 15 microns in diameter per unit volume of cerebral tissue decreased whereas the proportion of the vessels measuring up to 5 microns in diameter remained unchanged. The characteristics under study demonstrated the same line of changes in both spontaneous and experimental renal hypertension.
借助纹理分析系统，对自发性高血压大鼠和实验性肾性高血压大鼠直径达15微米的脑干微血管进行了组织学切片研究。高血压动物的脑组织单位体积血管直径、平均血管直径以及血管所占面积均减小，从而证明脑血管化密度降低。脑组织单位体积中直径为6至15微米的血管比例下降，而直径达5微米的血管比例保持不变。所研究的特征在自发性和实验性肾性高血压中均呈现相同的变化趋势。
