[自发性高血压大鼠脑内氧分压的分布]
[Distribution of oxygen tension in the brain of spontaneously hypertensive rats].
作者信息
Aleksandrova T B, Kilibaeva G S, Riasina T V, Demchenko I T, Moskalenko Iu E
出版信息
Biull Eksp Biol Med. 1987 Jan;103(1):15-7. doi: 10.1007/BF00840123.
PMID:3801641
Abstract
The distribution of cerebral tissue pO2 in spontaneously hypertensive Okamoto-Aoki rats (SHR) and normotensive Wistar-Kyoto rats (WK) was studied by means of polarographic microelectrodes 1-3 microns in diameter. SHR exhibited pO2 shifts towards low values and an increased heterogeneity of pO2 distribution in the cerebral tissue. Morphological studies of the brain have revealed diffuse and focal ischemia in the grey and white matter of the brain in SHR.
摘要
采用直径为1 - 3微米的极谱微电极研究了自发性高血压冈本 - 青木大鼠（SHR）和正常血压的Wistar - Kyoto大鼠（WK）脑组织中氧分压（pO2）的分布。SHR表现出脑组织中pO2向低值偏移且pO2分布的异质性增加。对大脑的形态学研究显示，SHR大脑的灰质和白质存在弥漫性和局灶性缺血。
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