胃肠道中不携带乳酸杆菌的小鼠的培育及应用。
The derivation and use of mice which do not harbour lactobacilli in the gastrointestinal tract.
作者信息
Tannock G W, Archibald R D
出版信息
Can J Microbiol. 1984 Jun;30(6):849-53. doi: 10.1139/m84-131.
DOI:10.1139/m84-131
PMID:6488105
Abstract
Penicillin treatment used in conjunction with germfree technology has allowed the derivation of a colony of BALB/c mice which do not harbour lactobacilli in the gastrointestinal tract. The animals continue to harbour Gram-negative anaerobes and coliforms, but not enterococci or filamentous segmented ileal microbes. Isolates of lactobacilli from rodents were able to colonize the gastrointestinal tract of the mice; and isolate from a fowl could not establish in these animals.
摘要
将青霉素治疗与无菌技术结合使用，已培育出一群胃肠道中不含乳酸杆菌的BALB/c小鼠。这些动物仍携带革兰氏阴性厌氧菌和大肠菌群，但不携带肠球菌或丝状分段回肠微生物。从啮齿动物分离出的乳酸杆菌能够在小鼠的胃肠道中定殖；而从禽类分离出的菌株则无法在这些动物体内定殖。
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