乳酸杆菌菌株在胆盐水解酶活性、胃肠道定植及小鼠宿主生长速率方面的比较。
Comparison of Lactobacillus strains with respect to bile salt hydrolase activity, colonization of the gastrointestinal tract, and growth rate of the murine host.
作者信息
Bateup J M, McConnell M A, Jenkinson H F, Tannock G W
机构信息
Department of Microbiology, University of Otago, Dunedin, New Zealand.
出版信息
Appl Environ Microbiol. 1995 Mar;61(3):1147-9. doi: 10.1128/aem.61.3.1147-1149.1995.
Abstract
The significance of bile salt hydrolase production by lactobacilli in the microecology of the murine intestinal tract has not been extensively studied previously. Assays of bile salt hydrolase (sodium taurocholate as substrate) associated with cell extracts of five Lactobacillus strains of murine origin gave a range of activities (from 915 nmol of cholate released per mg of protein per 30 min to none detected). All of the strains tested colonized the murine gastrointestinal tract equally well. The growth rates of mice were not affected by colonization of their intestinal tracts by lactobacilli whether or not the bacteria produced bile salt hydrolase.
摘要
此前，尚未对鼠源乳酸杆菌产生的胆汁盐水解酶在小鼠肠道微生态中的意义进行广泛研究。对五种鼠源乳酸杆菌菌株的细胞提取物相关的胆汁盐水解酶（以牛磺胆酸钠为底物）进行测定，得到了一系列活性数据（从每毫克蛋白质每30分钟释放915纳摩尔胆酸盐到未检测到活性）。所有测试菌株在小鼠胃肠道中的定殖情况同样良好。无论这些细菌是否产生胆汁盐水解酶，小鼠的生长速率都不受其肠道中乳酸杆菌定殖的影响。
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