Belghiti D, Hirbec G, Bernaudin J F, Pariente E A, Martin N
Cancer. 1984 Nov 15;54(10):2309-12. doi: 10.1002/1097-0142(19841115)54:10<2309::aid-cncr2820541043>3.0.co;2-4.
Glomerular metastases are rarely observed. Two cases of such metastases are reported. In one patient, proteinuria was detected and the diagnosis was made by kidney needle biopsy; light microscopy, immunofluorescence, and electron microscopy studies were performed. The second case was an autopsy finding. The histologic patterns were, respectively, an intracapillary metastasis and associated intra- and extracapillary metastases. These findings raise a number of questions concerning the early detection of such neoplastic diseases, the nature of primary tumors, and the mechanisms of malignant dissemination and glomerular localization.
肾小球转移瘤很少见。本文报告了两例此类转移瘤。其中一例患者检测到蛋白尿，通过肾穿刺活检确诊；进行了光镜、免疫荧光和电镜研究。第二例是尸检发现。组织学模式分别为毛细血管内转移以及相关的毛细血管内和毛细血管外转移。这些发现引发了许多关于此类肿瘤性疾病的早期检测、原发肿瘤的性质以及恶性播散和肾小球定位机制的问题。
