Huel G, Everson R B, Menger I
Environ Res. 1984 Oct;35(1):115-21. doi: 10.1016/0013-9351(84)90118-x.
Newborn and maternal hair samples were obtained from subjects occupationally exposed to heavy metals and from matched controls. The geometric means of levels of cadmium and lead in hair from exposed mothers and of cadmium in hair from transplacentally exposed newborns were twice as high as levels present in samples from controls. There was a positive correlation between levels of cadmium in maternal and newborn's hair, but no such correlation for lead. Despite statistically significant evidence of increased exposure to cadmium, no adverse health effects were documented in the small group of exposed newborns included in this study. Problems associated with exogenous contamination of hair by heavy metals and potential advantages of hair sampling for measuring fetal exposures to heavy metals are discussed.
从职业暴露于重金属的受试者及其匹配对照中获取新生儿和母亲的头发样本。暴露母亲头发中镉和铅的水平以及经胎盘暴露新生儿头发中镉的几何平均值是对照样本中水平的两倍。母亲和新生儿头发中的镉水平之间存在正相关,但铅不存在这种相关性。尽管有统计学上显著的证据表明镉暴露增加,但在本研究纳入的一小群暴露新生儿中未记录到不良健康影响。讨论了与头发受重金属外源性污染相关的问题以及头发采样在测量胎儿重金属暴露方面的潜在优势。