铝离子和铁离子在转铁蛋白结合位点上的竞争平衡。
The competitive equilibrium between aluminium and ferric ions for the binding sites of transferrin.
作者信息
Cochran M, Coates J, Neoh S
出版信息
FEBS Lett. 1984 Oct 15;176(1):129-32. doi: 10.1016/0014-5793(84)80926-6.
PMID:6489514
Abstract
Human transferrin is shown to bind 2 mol of aluminium per mol of protein using spectrophotometric titration. Competitive equilibrium between aluminium and ferric ions for transferrin binding sites is observed, and a value of 2.5 (+/- 0.4) X 10(15) M-1 is found for the apparent binding constant under physiological conditions.
摘要
通过分光光度滴定法表明，每摩尔人转铁蛋白可结合2摩尔铝。观察到铝离子和铁离子在转铁蛋白结合位点上的竞争平衡，发现在生理条件下，表观结合常数的值为2.5（±0.4）×10¹⁵ M⁻¹。
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