Sato S, Yajima A, Suzuki M
Gynecol Oncol. 1984 Oct;19(2):143-7. doi: 10.1016/0090-8258(84)90172-0.
A comparison of the 5-year relative survival rates has been made between cases of cancer of the uterine cervix treated with 226Ra low-dose-rate intracavitary irradiation and those treated with 60Co high-dose-rate intracavitary irradiation (using the remote afterloading system, RALS). External irradiation using LINAC was also administered in both groups. The 5-year relative survival rates of the low-dose-rate cases were 82.6, 55.4, 49.0, and 18.2% in stage I, II, III, and IV cases, respectively, whereas they were 97.4, 55.1, 56.8, and 29.0% in the respective high-dose-rate cases. The differences between the two groups were not statistically significant. Delayed radiation complications of the rectum were frequent in both groups (approximately 14%) and those of the urinary bladder were somewhat less frequent (approximately 8%). The incidence of such complications did not differ significantly between the two groups.
对采用镭-226低剂量率腔内照射治疗的子宫颈癌病例与采用钴-60高剂量率腔内照射(使用遥控后装系统,RALS)治疗的病例进行了5年相对生存率比较。两组均还采用直线加速器进行外照射。低剂量率病例在Ⅰ、Ⅱ、Ⅲ和Ⅳ期的5年相对生存率分别为82.6%、55.4%、49.0%和18.2%,而高剂量率病例在各期的相应生存率分别为97.4%、55.1%、56.8%和29.0%。两组之间的差异无统计学意义。两组中直肠迟发性放射并发症均较为常见(约14%),膀胱迟发性放射并发症则稍少见(约8%)。两组间此类并发症的发生率差异无显著性。