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[植入性塑料制品及血管内导管葡萄球菌感染的发病机制]

[Pathogenesis of staphylococcal infections of implanted plastics and intravascular catheters].

作者信息

Peters G

出版信息

Infection. 1984 Jul-Aug;12(4):235-9. doi: 10.1007/BF01645948.

DOI:10.1007/BF01645948
PMID:6490166
Abstract

Coagulase-negative staphylococci are the predominant organisms causing infection of intravasal catheters and implanted plastic material. They are able to adhere to and grow on polymer surfaces. During the course of colonization they produce large amounts of an extracellular slime substance by which they are finally covered completely. It is supposed that this matrix of slime protects the embedded staphylococci against antibacterial substances and natural host defenses. The slime substance is not a true capsule but is loosely bound to the staphylococcal cells. It seems to have interesting biological properties such as an adhesin-like function and the ability to inhibit the lymphoproliferative response of mononuclear cells.

摘要

凝固酶阴性葡萄球菌是引起血管内导管和植入性塑料材料感染的主要病原体。它们能够粘附在聚合物表面并在其上生长。在定植过程中,它们会产生大量细胞外黏液物质,最终完全被这种物质覆盖。据推测,这种黏液基质可保护嵌入其中的葡萄球菌免受抗菌物质和天然宿主防御机制的影响。黏液物质并非真正的荚膜,而是松散地附着在葡萄球菌细胞上。它似乎具有有趣的生物学特性,如类黏附素功能和抑制单核细胞淋巴增殖反应的能力。

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[Pathogenesis of staphylococcal infections of implanted plastics and intravascular catheters].[植入性塑料制品及血管内导管葡萄球菌感染的发病机制]
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本文引用的文献

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Indolent Staphylococcus albus or aureus bacteremia after ventriculoatriostomy. Role of foreign body in its initiation and perpetuation.脑室心房造口术后惰性白色葡萄球菌或金黄色葡萄球菌菌血症。异物在其发生和持续存在中的作用。
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Microbial colonization of prosthetic devices. I. Microtopographical characteristics of intravenous catheters as detected by scanning electron microscopy.人工装置的微生物定植。I. 静脉导管微观形貌特征的扫描电子显微镜检测
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Permanent pacemaker infections: characterization and management.永久性起搏器感染:特征与管理
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7
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Aerobic and anaerobic bacteria in deep infections after total hip arthroplasty: differential diagnosis between infectious and non-infectious loosening.全髋关节置换术后深部感染中的需氧菌和厌氧菌:感染性与非感染性松动的鉴别诊断
Clin Orthop Relat Res. 1981 Jan-Feb(154):201-7.
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