Moroder L, Drees F, Jaeger E, Wünsch E
Hoppe Seylers Z Physiol Chem. 1978 Feb;359(2):147-53.
The synthesis of the tridecapeptide amide corresponding to and 11-leucine analog of human minigastrin I is decribed. The fully protected peptide derivative was obtained by assembly of three suitably protected fragments corresponding to the sequences 1-6, 7-9 and 10-13 by the carbodiimide/N-hydroxysuccinimide method.
本文描述了与人类胃泌素 I 的 11 - 亮氨酸类似物相对应的十三肽酰胺的合成。通过碳二亚胺/N - 羟基琥珀酰亚胺法,将对应于序列 1 - 6、7 - 9 和 10 - 13 的三个适当保护的片段组装,得到了完全保护的肽衍生物。