墨西哥婴儿中艰难梭菌及其细胞毒素的流行情况。
Prevalence of Clostridium difficile and its cytotoxin in infants in Mexico.
作者信息
Torres J F, Cedillo R, Sánchez J, Dillman C, Giono S, Muñoz O
出版信息
J Clin Microbiol. 1984 Aug;20(2):274-5. doi: 10.1128/jcm.20.2.274-275.1984.
The incidence of Clostridium difficile and its cytotoxic activity were determined in the feces of 122 children under 1 year of age. Samples were obtained from children receiving antibiotics and with (52 cases) or without (26 cases) diarrhea, from children with diarrhea who did not receive antibiotics (22 cases), and from healthy children (22 cases). Isolation of C. difficile in feces from children in all groups was similar (mean 23.4%) except for the group with non-antibiotic-associated diarrhea (4.5%). In both groups of children receiving antibiotics, with or without diarrhea, the cytotoxin was detected in 7.6% of the cases. In the group with non-antibiotic-associated diarrhea, none of the samples was positive for cytotoxicity. In healthy children, cytotoxin was positive in 4.5% of the cases.
测定了122名1岁以下儿童粪便中艰难梭菌的发生率及其细胞毒性活性。样本取自接受抗生素治疗且有（52例）或无（26例）腹泻的儿童、未接受抗生素治疗的腹泻儿童（22例）以及健康儿童（22例）。除非抗生素相关性腹泻组（4.5%）外，所有组儿童粪便中艰难梭菌的分离率相似（平均23.4%）。在接受抗生素治疗的两组儿童中，无论有无腹泻，7.6%的病例检测到细胞毒素。在非抗生素相关性腹泻组中，所有样本的细胞毒性均为阴性。在健康儿童中，4.5%的病例细胞毒素呈阳性。
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