Koulischer L, Gillerot Y
J Genet Hum. 1984 Sep;32(4):265-9.
The usual indications of amniocentesis for prenatal diagnosis are briefly reviewed. Some situations which are note included in these usual indications are discussed: mothers of 34 years, young aunts of a trisomic child, patients with a previous aborted conceptus diagnosed as trisomic by histological examination of the placenta or tissue culture. It is anticipated that, if accepted, these "unusual" criteria would not overload a given laboratory with an excess of analysis, and would certainly relief anxiety of motivated couples.
本文简要回顾了羊膜穿刺术用于产前诊断的常见指征。文中还讨论了一些未包含在这些常见指征中的情况:34岁的母亲、三体患儿的年轻阿姨、曾有过经胎盘组织学检查或组织培养诊断为三体的流产胚胎的患者。预计,如果这些“不寻常”的标准被接受,不会使特定实验室因过多的分析而不堪重负,并且肯定会减轻有意愿的夫妇的焦虑。