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Uptake and hepatotoxicity of 1,1-dichloroethylene by the isolated blood-perfused rat liver.

作者信息

Reichert D, Henschler D

出版信息

Int Arch Occup Environ Health. 1978 May 12;41(3):169-78. doi: 10.1007/BF00572889.

DOI:10.1007/BF00572889
PMID:649207
Abstract
摘要

相似文献

1
Uptake and hepatotoxicity of 1,1-dichloroethylene by the isolated blood-perfused rat liver.1,1-二氯乙烯在离体血液灌注大鼠肝脏中的摄取及肝毒性
Int Arch Occup Environ Health. 1978 May 12;41(3):169-78. doi: 10.1007/BF00572889.
2
Role of liver glutathione in 1,1-dichloroethylene metabolism and hepatotoxicity in intact rats and isolated perfused rat liver.
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3
Pharmacokinetics of vinylidene chloride.偏二氯乙烯的药代动力学
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4
The use of inhalation techniques to assess the kinetic constants of 1,1-dichloroethylene metabolism.使用吸入技术评估1,1 - 二氯乙烯代谢的动力学常数。
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The significance of multiple detoxification pathways for reactive metabolites in the toxicity of 1,1-dichloroethylene.多种解毒途径对1,1-二氯乙烯毒性中活性代谢物的意义。
Toxicol Appl Pharmacol. 1980 Mar 15;52(3):422-32. doi: 10.1016/0041-008x(80)90337-3.
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Saturable metabolism and the acute toxicity of 1,1-dichloroethylene.1,1 - 二氯乙烯的饱和代谢与急性毒性
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7
Tissue distribution and covalent binding of [14C]1,1-dichloroethylene in mice: in vivo and in vitro studies.
Adv Exp Med Biol. 1986;197:903-10. doi: 10.1007/978-1-4684-5134-4_86.
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Carcinogenesis. 1984 Dec;5(12):1629-36. doi: 10.1093/carcin/5.12.1629.
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Effect of administrative vehicle on oral 1,1-dichloroethylene toxicity.行政用车对口服1,1 - 二氯乙烯毒性的影响。
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引用本文的文献

1
Inhalation pharmacokinetics of 1,2-dichloroethane after different dietary pretreatments of male Sprague-Dawley rats.雄性斯普拉格-道利大鼠经不同饮食预处理后1,2-二氯乙烷的吸入药代动力学
Arch Toxicol. 1986 Oct;59(3):127-34. doi: 10.1007/BF00316320.
2
Role of liver glutathione in 1,1-dichloroethylene metabolism and hepatotoxicity in intact rats and isolated perfused rat liver.
Arch Toxicol. 1978 Dec 28;41(3):169-78. doi: 10.1007/BF00354088.
3
Pharmacokinetics of halogenated ethylenes in rats.卤代乙烯在大鼠体内的药代动力学

本文引用的文献

1
The dominant role of the liver in plasma protein synthesis; a direct study of the isolated perfused rat liver with the aid of lysine-epsilon-C14.肝脏在血浆蛋白合成中的主导作用；借助赖氨酸-ε-C14对离体灌注大鼠肝脏进行的直接研究。
J Exp Med. 1951 Nov;94(5):431-53. doi: 10.1084/jem.94.5.431.
2
A RAPID METHOD FOR THE SIMULTANEOUS DETERMINATION OF ACETALDEHYDE AND ETHANOL IN BLOOD USING GAS CHROMATOGRAPHY.一种使用气相色谱法同时测定血液中乙醛和乙醇的快速方法。
Q J Stud Alcohol. 1964 Sep;25:498-510.
3
THE METABOLISM OF 36C1-LABELLED TRICHLOROETHYLENE AND TETRACHLOROETHYLENE IN THE RAT.
Arch Toxicol. 1979 Jun 8;42(2):123-36. doi: 10.1007/BF00316492.
4
Molecular mechanism of 1,1-dichloroethylene toxicity: excreted metabolites reveal different pathways of reactive intermediates.1,1-二氯乙烯毒性的分子机制：排泄代谢产物揭示了反应性中间体的不同途径。
Arch Toxicol. 1979 Jul 11;42(3):159-69. doi: 10.1007/BF00353707.
大鼠体内36C1标记的三氯乙烯和四氯乙烯的代谢
Biochem Pharmacol. 1963 Aug;12:795-802. doi: 10.1016/0006-2952(63)90109-6.
4
[ON A SPECIFIC EFFECT OF GLUCAGON ON THE EMBDEN-MEYERHOF CHAIN IN THE LIVER. EXPERIMENTS ON THE ISOLATED PERFUSED RAT LIVER].[关于胰高血糖素对肝脏中糖酵解途径的特定作用。对离体灌注大鼠肝脏的实验]
Biochem Z. 1963 Aug 14;337:510-8.
5
Metabolism of trichloroethylene in liver microsomes. 3. Induction of the enzymic activity and its effect on excretion of metabolites.三氯乙烯在肝微粒体中的代谢。3. 酶活性的诱导及其对代谢物排泄的影响。
J Pharmacol Exp Ther. 1967 Sep;157(3):574-80.
6
Metabolism of trichloroethylene in liver microsomes. II. Identification of the reaction product as chloral hydrate.三氯乙烯在肝微粒体中的代谢。II. 反应产物为水合氯醛的鉴定。
Mol Pharmacol. 1965 Nov;1(3):247-54.
7
Angiosarcoma of liver in the manufacture of polyvinyl chloride.氯乙烯制造过程中发生的肝血管肉瘤。
J Occup Med. 1974 Mar;16(3):150-1.
8
[Automatic evaluation of sample composition and correction factors in computerized blood alcohol analysis (author's transl)].[计算机化血液酒精分析中样本成分和校正因子的自动评估（作者译）]
Z Rechtsmed. 1973 Jun 29;72(4):278-82. doi: 10.1007/BF02114885.
9
Biochemical effects of 1,1-dichloroethylene in rats: comparison with carbon tetrachloride and 1,2-dichloroethylene.1,1-二氯乙烯对大鼠的生化效应：与四氯化碳和1,2-二氯乙烯的比较
Toxicol Appl Pharmacol. 1972 Nov;23(3):501-10. doi: 10.1016/0041-008x(72)90052-x.
10
Metabolism of trichloroethylene in liver microsomes. I. Characteristics of the reaction.三氯乙烯在肝微粒体中的代谢。I. 反应特性。
Mol Pharmacol. 1965 Nov;1(3):239-46.