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Pharmacokinetics of halogenated ethylenes in rats.

作者信息

Filser J G, Bolt H M

出版信息

Arch Toxicol. 1979 Jun 8;42(2):123-36. doi: 10.1007/BF00316492.

DOI:10.1007/BF00316492
PMID:485853
Abstract
摘要

相似文献

1
Pharmacokinetics of halogenated ethylenes in rats.卤代乙烯在大鼠体内的药代动力学
Arch Toxicol. 1979 Jun 8;42(2):123-36. doi: 10.1007/BF00316492.
2
Reactive metabolites and carcinogenicity of halogenated ethylenes.
Biochem Pharmacol. 1982 Jan 1;31(1):1-4. doi: 10.1016/0006-2952(82)90227-1.
3
Metabolism of halogenated ethylenes.卤代乙烯的代谢
Environ Health Perspect. 1977 Dec;21:91-7. doi: 10.1289/ehp.772191.
4
Mutagenic and alkylating metabolites of halo-ethylenes, chlorobutadienes and dichlorobutenes produced by rodent or human liver tissues. Evidence for oxirane formation by P450-linked microsomal mono-oxygenases.啮齿动物或人类肝脏组织产生的卤代乙烯、氯丁二烯和二氯丁烯的诱变和烷基化代谢产物。细胞色素P450相关微粒体单加氧酶形成环氧乙烷的证据。
Arch Toxicol. 1979 Feb 23;41(4):249-77. doi: 10.1007/BF00296896.
5
Reductive metabolism of halothane and hepatotoxicity.
Anesthesiology. 1979 Nov;51(5):486. doi: 10.1097/00000542-197911000-00042.
6
Time-course of formation of volatile reductive metabolites of halothane in humans and an animal model.
Br J Anaesth. 1980 Mar;52(3):331-6.
7
Mutagenicity studies with volatile metabolites of halothane.氟烷挥发性代谢物的致突变性研究。
Anesthesiology. 1979 Nov;51(5):424-9. doi: 10.1097/00000542-197911000-00011.
8
Pharmacokinetics and ecodisposition of polyhalogenated hydrocarbons: aspects and concepts.
Drug Metab Rev. 1980;11(2):149-90. doi: 10.3109/03602538008994024.
9
The metabolism and disposition of halogenated aromatics.
Ann N Y Acad Sci. 1979 May 31;320:131-7. doi: 10.1111/j.1749-6632.1979.tb56596.x.
10
Mutagenesis and carcinogenesis of halogenated ethylenes.卤代乙烯的诱变与致癌作用
Ann N Y Acad Sci. 1988;534:679-93. doi: 10.1111/j.1749-6632.1988.tb30158.x.

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The Physical Adsorption of Gelatinized Starch with Tannic Acid Decreases the Inhibitory Activity of the Polyphenol against α-Amylase.糊化淀粉与单宁酸的物理吸附降低了多酚对α-淀粉酶的抑制活性。
Foods. 2021 May 28;10(6):1233. doi: 10.3390/foods10061233.
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Species-specific pharmacokinetics of styrene in rat and mouse.苯乙烯在大鼠和小鼠体内的种属特异性药代动力学。
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Characteristics of haloethylene-induced acetonemia in rats.大鼠中卤代乙烯诱导的丙酮血症的特征

本文引用的文献

1
Chemical reactivity, metabolic oxirane formation and biological reactivity of chlorinated ethylenes in the isolated perfused rat liver preparation.氯化乙烯在离体灌注大鼠肝脏制剂中的化学反应性、代谢环氧乙烷的形成及生物活性。
Biochem Pharmacol. 1975 Oct 1;24(19):1829-34. doi: 10.1016/0006-2952(75)90468-2.
2
Disposition of (1,2-14C) vinyl chloride in the rat.大鼠体内（1,2-¹⁴C）氯乙烯的分布情况。
Arch Toxicol. 1976 Jun 8;35(3):153-62. doi: 10.1007/BF00293562.
3
Incubation of 14C-trichloroethylene vapor with rat liver microsomes: uptake of radioactivity and covalent protein binding of metabolites.
Arch Toxicol. 1980 Jul;45(2):109-16. doi: 10.1007/BF01270908.
4
Malignant tumors after chronic exposure to vinyl chloride.长期接触氯乙烯后的恶性肿瘤。
J Cancer Res Clin Oncol. 1981;102(1):1-11. doi: 10.1007/BF00410529.
5
Inhalation pharmacokinetics based on gas uptake studies. III. A pharmacokinetic assessment in man of "peak concentrations" of vinyl chloride.基于气体摄取研究的吸入药代动力学。III. 人体中氯乙烯“峰值浓度”的药代动力学评估。
Arch Toxicol. 1981 Nov;48(4):213-28. doi: 10.1007/BF00319650.
6
Formation of pre-neoplastic hepatocellular foci by vinyl fluoride in newborn rats.新生大鼠中氟乙烯诱导形成癌前肝细胞灶。
Arch Toxicol. 1981 Mar;47(1):71-3. doi: 10.1007/BF00297134.
7
Inhalation pharmacokinetics based on gas uptake studies. II. Pharmacokinetics of acetone in rats.基于气体摄取研究的吸入药代动力学。II. 丙酮在大鼠体内的药代动力学。
Arch Toxicol. 1981 Jul;47(4):293-304. doi: 10.1007/BF00332395.
8
Inhalation pharmacokinetics based on gas uptake studies. I. Improvement of kinetic models.基于气体摄取研究的吸入药代动力学。I. 动力学模型的改进。
Arch Toxicol. 1981 Jul;47(4):279-92. doi: 10.1007/BF00332394.
9
Covalent binding of drug metabolites to DNA--a tool of predictive value?药物代谢产物与DNA的共价结合——一种具有预测价值的工具？
Arch Toxicol. 1980 Nov;46(1-2):171-80. doi: 10.1007/BF00361255.
10
Increased acetone exhalation induced by metabolites of halogenated C1 and C2 compounds.卤代C1和C2化合物的代谢产物引起丙酮呼出增加。
Arch Toxicol. 1982 Jan;49(2):107-16. doi: 10.1007/BF00332358.
用大鼠肝微粒体对14C-三氯乙烯蒸汽进行温育：放射性摄取及代谢产物与蛋白质的共价结合。
Int Arch Occup Environ Health. 1977 Jun 30;39(2):103-11. doi: 10.1007/BF00380890.
4
Pharmacokinetics of vinyl chloride in the rat.大鼠体内氯乙烯的药代动力学
Toxicology. 1977 Apr;7(2):179-88. doi: 10.1016/0300-483x(77)90063-4.
5
Chemical reactivity, biotransformation, and toxicity of polychlorinated aliphatic compounds.多氯脂肪族化合物的化学反应性、生物转化及毒性
CRC Crit Rev Toxicol. 1976 Oct;4(4):395-409. doi: 10.1080/10408447609164019.
6
Metabolism and pharmacokinetic profile of vinylidene chloride in rats following oral administration.大鼠口服偏二氯乙烯后的代谢及药代动力学特征
Toxicol Appl Pharmacol. 1978 Sep;45(3):821-35. doi: 10.1016/0041-008x(78)90173-4.
7
Uptake and hepatotoxicity of 1,1-dichloroethylene by the isolated blood-perfused rat liver.1,1-二氯乙烯在离体血液灌注大鼠肝脏中的摄取及肝毒性
Int Arch Occup Environ Health. 1978 May 12;41(3):169-78. doi: 10.1007/BF00572889.
8
Resolution of dose-response toxicity data for chemicals requiring metabolic activation: example--vinyl chloride.需要代谢活化的化学物质的剂量-反应毒性数据解析：示例——氯乙烯
Toxicol Appl Pharmacol. 1978 Jun;44(3):581-91. doi: 10.1016/0041-008x(78)90266-1.
9
Pharmacokinetics of vinyl chloride.
Gen Pharmacol. 1978;9(2):91-5. doi: 10.1016/0306-3623(78)90006-x.
10
Rat liver microsomal uptake and irreversible protein binding of [1,2-14C]vinyl bromide.[1,2-¹⁴C]溴乙烯在大鼠肝脏微粒体中的摄取及不可逆蛋白结合
Toxicol Appl Pharmacol. 1978 Jun;44(3):481-9. doi: 10.1016/0041-008x(78)90256-9.