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[圆窗膜自发性穿孔——突发性耳聋的主要原因?]

[Spontaneous perforation of the membrane of the round window--a major cause of sudden deafness?].

作者信息

Arndt H J

出版信息

Laryngol Rhinol Otol (Stuttg). 1984 Sep;63(9):439-44.

PMID:6492958
Abstract

In 1983, 45 out of 63 clinically treated patients with sudden hearing loss underwent an exploratory tympanotomy. In 27 cases (60%) a perforation of the round window membrane was found, whereas in 18 cases (40%) the round window membrane was intact and there was no perilymph fistula. From 1982 to the end of 1983 30 perforations of the round window membrane were found which are reported here, most of them being spontaneous perforations without any preceding trauma. Audiometrically, hearing losses were found ranging from medium to high degree. These included all types of hard hearing, such as loss of high or low tones and losses over all frequency ranges to total deafness. All patients complained of tinnitus. One-third of the patients with perforated membrane had dizziness or vertigo combined with disturbances of balance. Treatment consisted of sealing the round window membrane with a plug of fascia or periostium. When the patients were discharged, or shortly after their discharge, audiometry revealed normal hearing in three patients, improved hearing in 8 patients, no change in 14 patients, and further deterioration in 3 patients. In 8 patients with perforated membrane, the sudden hearing loss had occurred 1 to 12 months back and in 6 patients only 8 to 30 days ago. The study will continue, but we can already see from the present results that every sudden hearing loss should be examined for a possible spontaneous perforation of the round window membrane. For this reason, exploration of the round window should be done within the first few days. The study yields new knowledge of the pathogenesis of the sudden hearing loss.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

1983年,63例接受临床治疗的突发性听力损失患者中有45例接受了探查性鼓室切开术。27例(60%)发现圆窗膜穿孔,而18例(40%)圆窗膜完整且无外淋巴瘘。从1982年到1983年底,共发现30例圆窗膜穿孔,在此报告,其中大多数为自发性穿孔,无前驱外伤史。听力测定显示听力损失从中度到高度不等。包括各种类型的听力减退,如高音或低音丧失以及全频听力损失直至全聋。所有患者均有耳鸣主诉。三分之一的圆窗膜穿孔患者伴有头晕或眩晕以及平衡障碍。治疗方法是用一块筋膜或骨膜堵塞圆窗膜。患者出院时或出院后不久,听力测定显示3例患者听力正常,8例患者听力改善,14例患者听力无变化,3例患者听力进一步恶化。8例圆窗膜穿孔患者的突发性听力损失发生在1至12个月前,6例患者仅在8至30天前发病。研究将继续进行,但从目前的结果我们已经可以看出,每例突发性听力损失都应检查是否存在圆窗膜的自发性穿孔。因此,应在最初几天内对圆窗进行探查。该研究为突发性听力损失的发病机制提供了新的认识。(摘要截选至250字)

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