长期使用氟哌啶醇治疗未能改变大鼠脑纹状体、嗅结节和伏隔核区域内胆囊收缩素的水平。
Failure of chronic haloperidol treatment to alter levels of cholecystokinin in the rat brain striatum and olfactory tuberclenucleus accumbens area.
作者信息
Gysling K, Beinfeld M C
出版信息
Neuropeptides. 1984 Sep;4(5):421-3. doi: 10.1016/0143-4179(84)90117-3.
PMID:6493457
Abstract
We have studied the effect of chronic haloperidol (HAL) treatment on CCK-8 levels in two rat brain regions. HAL administration using two different protocols, daily injections and infusion with subcutaneously implanted minipumps, did not produce any significant changes in CCK-8 levels in the striatum or olfactory tubercle-nucleus accumbens area.
摘要
我们研究了慢性给予氟哌啶醇（HAL）对大鼠两个脑区中胆囊收缩素-8（CCK-8）水平的影响。采用两种不同给药方案给予HAL，即每日注射以及通过皮下植入微型泵输注，均未使纹状体或嗅结节-伏隔核区域的CCK-8水平发生任何显著变化。
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