Pakasa M, Kalengayi M R
Tropenmed Parasitol. 1984 Sep;35(3):193-5.
Morphological and aetiological aspects of 88 renal biopsies for nephrotic syndrome (NS) from Zaire are reported. About 52% were associated with a single or multiple infectious diseases particularly of parasitic origin. Three additional cases were associated with local non infectious conditions including the sickle cell disease and the abuse of mercuric-containing compounds. However, the histopathology was indistinguishable in both "idiopathic" and parasite-associated NS, and showed a wide range of common glomerulopathies. We conclude that the glomerular damage of the majority of NS from this area is probably mediated by nephritogenic immune complexes induced by several parasitic diseases, and would need further immunocytochemical investigations.
报告了来自扎伊尔的88例肾病综合征（NS）肾活检的形态学和病因学方面。约52%与单一或多种传染病相关，尤其是寄生虫源性传染病。另外3例与局部非感染性疾病相关，包括镰状细胞病和汞化合物滥用。然而，“特发性”和寄生虫相关NS的组织病理学无法区分，且显示出广泛的常见肾小球病。我们得出结论，该地区大多数NS的肾小球损伤可能由几种寄生虫病诱导的致肾炎免疫复合物介导，需要进一步进行免疫细胞化学研究。
