Sørensen S S, Nielsen J B, Nørgaard J P, Knudsen L M, Djurhuus J C
Urol Res. 1984;12(4):205-8. doi: 10.1007/BF00256804.
Fifty-six patients were investigated by repetitive cystometry in the supine or sitting position. The incidence of detrusor hyperreflexia and the circumstances under which it was found did not differ from previous studies. The cystometry data concerning volumes showed a remarkable degree of variability. Values for first sensation and maximal capacity could vary more than 500%. An increment from the first cystometry to the fourth was consistently found. The increments were most pronounced when cystometry with fast filling followed cystometry with medium filling regardless of the patient's position. The major factor in the changes is considered to be the patient's adaptation to the investigational situation. This finding might have major significance in the evaluation of drug studies where repeated cystometries with different time intervals are used.
56名患者在仰卧位或坐位接受了重复膀胱测压检查。逼尿肌反射亢进的发生率及其发现时的情况与先前研究并无差异。膀胱测压的容量数据显示出显著的变异性。首次感觉和最大容量的值可能相差超过500%。从第一次膀胱测压到第四次，始终发现有增加。无论患者体位如何，当快速充盈膀胱测压紧跟中等充盈膀胱测压时，增加最为明显。变化的主要因素被认为是患者对检查情况的适应。这一发现可能对评估使用不同时间间隔进行重复膀胱测压的药物研究具有重要意义。
