Belyĭ V P, Gonsales B B
Zh Vyssh Nerv Deiat Im I P Pavlova. 1984 Jul-Aug;34(4):685-93.
The effect of duration of stimulus addressed to the lateral hypothalamus on self-stimulation (SS) frequency was studied in rabbits. In the first experimental series, durations preferred by the animals were determined. Histograms of pression durations were obtained, and modal (Tm) and mean (T mean) durations were assessed. In the second series, stimuli were used of fixed duration equal to Tm, T mean and multiples to them--longer and shorter impulse bursts. Three types of distribution histograms of pression durations were obtained, which differed from each other by the form of the envelop as well as by variation coefficients of deviation of self regulated durations from the mean (T mean). These parameters were of a character of individual differences independently from localization of the stimulating electrodes tips. SS frequency was maximal when stimulation durations were 2 Tm and 1/2-1/4 T mean. Prolongation or shortening of the stimulation led to weakening of its reinforcing effect. The concept is discussed of two-component mechanism of reaction to stimulation of the SS hypothalamic zones: motivational excitation against the background of current action and positive reinforcement in post-stimulation period.
研究了刺激家兔外侧下丘脑的持续时间对自我刺激（SS）频率的影响。在第一个实验系列中，确定了动物偏好的持续时间。获得了按压持续时间的直方图，并评估了众数（Tm）和平均（T均值）持续时间。在第二个系列中，使用了固定持续时间的刺激，其等于Tm、T均值及其倍数——更长和更短的脉冲串。获得了三种类型的按压持续时间分布直方图，它们在包络形式以及自我调节持续时间相对于平均值（T均值）的偏差变异系数方面彼此不同。这些参数具有个体差异的特征，与刺激电极尖端的定位无关。当刺激持续时间为2Tm和1/2 - 1/4T均值时，SS频率最高。刺激的延长或缩短会导致其强化作用减弱。讨论了对下丘脑SS区刺激反应的双成分机制的概念：当前作用背景下的动机激发和刺激后时期的正强化。
