Ravi S D, Dorus W, Park Y N, Collins M C, Reid R W, Borge G F
Am J Psychiatry. 1984 Nov;141(11):1445-8. doi: 10.1176/ajp.141.11.1445.
Results of the dexamethasone suppression test (DST) in 30 alcoholic patients tested on day 5 and again on day 25 after their last drink are presented. Nineteen patients (63%) failed to suppress cortisol on day 5; three (11%) failed to suppress cortisol on day 25. Depressive symptoms, measured by the Beck Depression Inventory, were significantly correlated with DST results; the lifetime diagnosis of depressive illness was not. The authors conclude that the DST is not useful in detecting primary affective disorders during the early phase of withdrawal from alcohol.
本文呈现了30名酒精成瘾患者在最后一次饮酒后第5天和第25天进行地塞米松抑制试验（DST）的结果。19名患者（63%）在第5天未能抑制皮质醇分泌；3名患者（11%）在第25天未能抑制皮质醇分泌。通过贝克抑郁量表测量的抑郁症状与DST结果显著相关；而抑郁疾病的终生诊断结果则不然。作者得出结论，DST在酒精戒断早期检测原发性情感障碍方面并无用处。
