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猫贾第虫病:自然感染和人工感染的观察

Feline giardiasis: observations on natural and induced infections.

作者信息

Kirkpatrick C E, Farrell J P

出版信息

Am J Vet Res. 1984 Oct;45(10):2182-8.

PMID:6497121
Abstract

The excretion of Giardia sp cysts in the feces of naturally and artificially infected cats fluctuated sporadically, and cysts were undetectable several times during 7 weeks of observation. The mean prepatent period for Giardia infection in 7 cats was 9.6 days (range, 5 to 16 days). The amount of the cyst inoculum did not appear to affect the length of the prepatent period. Six of 11 cats had clinical signs consistent with those of giardiasis. Clinical signs and cyst excretion were eliminated after treatment with metronidazole or furazolidone. Moderate oral or parenteral doses of corticosteroids produced little, if any, alteration in the infection. Postmortem examination of 1 inoculated cat revealed Giardia trophozoites in the jejunum and upper portion of the ileum but not in the duodenum, lower portion of the ileum, cecum, or colon. Giardia cysts isolated from cat feces produced infection in Mongolian gerbils but not in C57BL/6J mice.

摘要

自然感染和人工感染的猫粪便中贾第虫属囊肿的排泄情况呈零星波动,在7周的观察期内有几次未检测到囊肿。7只猫感染贾第虫的平均潜伏期为9.6天(范围为5至16天)。囊肿接种量似乎不影响潜伏期的长短。11只猫中有6只出现了与贾第虫病相符的临床症状。甲硝唑或呋喃唑酮治疗后,临床症状和囊肿排泄消失。中等剂量的口服或肠胃外皮质类固醇对感染几乎没有影响(如果有影响的话也很小)。对1只接种的猫进行尸检发现,空肠和回肠上部有贾第虫滋养体,但十二指肠、回肠下部、盲肠或结肠中没有。从猫粪便中分离出的贾第虫囊肿可使蒙古沙鼠感染,但不能使C57BL/6J小鼠感染。

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