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全球疟疾控制的现状与未来展望

Present status and future prospects for malaria control in the world.

作者信息

Lepes T

出版信息

Ann Acad Med Singap. 1984 Apr;13(2):163-70.

PMID:6497316
Abstract

The potential of residual insecticides with their direct action against the sporogonic cycle of plasmodia prompted the idea of possible eradication of malaria. In the early fifties health administrators supported by technicians favoured the control of endemic diseases through "mass campaigns". In such an atmosphere, at the 8th World Health Assembly held in Mexico in 1955 a resolution was adopted urging member states to initiate health programmes aimed at eradicating malaria. Initial spectacular results continued for ten years, but the progress slowed down considerably in the late sixties due to a number of technical, operational and administrative problems encountered in many countries. Nevertheless, malaria was eradicated in 37 countries and territories, thus freeing the population of some 500 million from the risk of infection. During the period 1972-1977 serious resurgence of malaria affected a number of countries in South East Asia, Central America and Turkey. Energetic counter measures have brought down malaria to a level which is far from being under control. At the same time in Africa, south of the Sahara, practically no organised control of malaria is being carried out. While malaria morbidity is rising, the policy of national health administrations is to carry out malaria control applying the strategy of Primary Health Care. However, in view of the multiple difficulties countries are facing much more flexibility and an epidemiological approach are required at this stage. Possible modalities for action are discussed in the paper in more detail.

摘要

残留杀虫剂对疟原虫孢子生殖周期具有直接作用,这一特性激发了根除疟疾的想法。20世纪50年代初,在技术人员的支持下,卫生管理人员倾向于通过“大规模运动”来控制地方病。在这样的氛围中,1955年于墨西哥举行的第8届世界卫生大会通过了一项决议,敦促成员国启动旨在根除疟疾的卫生项目。最初的显著成果持续了十年,但到了60年代后期,由于许多国家遇到的一些技术、操作和管理问题,进展大幅放缓。尽管如此,37个国家和地区根除了疟疾,从而使约5亿人口摆脱了感染风险。在1972年至1977年期间,疟疾的严重复发影响了东南亚、中美洲和土耳其的一些国家。积极的应对措施已将疟疾发病率降低到远未得到控制的水平。与此同时,在撒哈拉以南的非洲地区,实际上并未开展有组织的疟疾防治工作。虽然疟疾发病率在上升,但各国卫生管理部门的政策是采用初级卫生保健战略来开展疟疾防治工作。然而,鉴于各国面临的多重困难,现阶段需要更大的灵活性和采用流行病学方法。本文将更详细地讨论可能的行动方式。

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