Kaidbey K H, Messenger J L
Arch Dermatol. 1984 Nov;120(11):1441-8.
Eight patients had a chronic photodermatitis of five to 19 years' duration. The clinical and photobiological features were consistent with the pattern observed in persistent light reactors. Severity and clinical presentation, however, were quite variable, ranging from a few isolated papules to extensive lichenification involving the entire exposed skin. Three had positive photopatch tests to halogenated salicylanilides, while the remaining five reacted to musk ambrette. Exposure of the uninvolved skin to UV-B or solar-simulated radiation provoked abnormal delayed papular or infiltrated reactions. Histological evaluation of these reactions in three cases disclosed moderate to dense perivascular lymphocytic infiltrates with occasional eosinophils, focal exocytosis, and epidermal spongiosis. We conclude that persistent light reactivity associated with photoallergic contact dermatitis shows a spectrum of disease activity and photosensitivity. Recognition of the subtle forms of this disease is important.
8例患者患有慢性光性皮炎，病程为5至19年。临床和光生物学特征与持续性光反应者中观察到的模式一致。然而，严重程度和临床表现差异很大，从少数孤立的丘疹到累及整个暴露皮肤的广泛苔藓化。3例对卤化水杨酰苯胺光斑试验呈阳性，其余5例对葵子麝香有反应。未受累皮肤暴露于UV-B或模拟阳光辐射会引发异常的延迟丘疹或浸润反应。对3例此类反应的组织学评估显示，血管周围有中度至密集的淋巴细胞浸润，偶见嗜酸性粒细胞、局灶性细胞外渗和表皮海绵形成。我们得出结论，与光变应性接触性皮炎相关的持续性光反应表现出一系列疾病活动和光敏性。认识这种疾病的细微形式很重要。
