Viktorov A V, Grepachevskiĭ A A, Bergel'son L D
Bioorg Khim. 1984 Jul;10(7):935-9.
The phage T7 DNA complexes with various phospholipids (PL) were studied by 31P NMR at PL/nucleotide molar ratio of 2 : 1. Using a phosphatidylcholine thion analogue, the contributions of PL and DNA into the 31P NMR spectrum of the complex were estimated. It was found that PL-DNA interaction results in partial immobilizing ability of PL depends on their structure, increasing in the following row: phosphatidylcholine-phosphatidylethanolamine less than sphingomyelin less than or equal to ternary mixture of these PL. The data obtained are indicative of nonequivalent binding of DNA with various PL species.
在磷脂（PL）与核苷酸摩尔比为2∶1的条件下，利用31P核磁共振技术研究了噬菌体T7 DNA与各种磷脂形成的复合物。使用硫代磷脂酰胆碱类似物，估算了磷脂和DNA对复合物31P核磁共振谱的贡献。研究发现，磷脂与DNA的相互作用导致磷脂的部分固定化，其固定化能力取决于磷脂的结构，按以下顺序增强：磷脂酰胆碱＜磷脂酰乙醇胺＜鞘磷脂≤这些磷脂的三元混合物。所得数据表明，DNA与不同种类磷脂的结合并不等效。
