Shiogai T, Takeuchi K
No To Shinkei. 1984 Aug;36(8):781-7.
Walker states that the incidence of brain death accounts for approximately 1% of all deaths, so that brain death is a common state. According to Jennett et al, the occurrence of brain death is now a relatively frequent event, with about 4000 cases each year in Britain. But the actual circumstances of brain death can not be discovered from any published report. During the last 11 years (1973-1983) at Kyorin University Hospital, we studied 121 cases diagnosed as brain death according to Japanese criteria. The Japanese criteria requires that the pathology be a gross primary brain lesion, so did not concern ourselves with brain deaths due to secondary brain damage. We analysed the factors associated with brain death, that is the annual incidence, age, sex distribution, primary diagnosis and elapsed time from brain death to cardiac death. The increasing incidence of brain death in the last 5 years is probably due to a rise in severely brain-damaged patients (Table 1). In the age distribution, the high number of patients in their fifties presumably reflects the human age tendency for traumatic and vascular disorders respectively (Fig. 1 and Table 2). The fact that males predominate relates to the greater risk faced regarding cerebral trauma (Table 3). The primary diagnoses were cerebrovascular accidents in 60% of the cases especially subarachnoid hemorrhage in 41%, head injury in 31% and brain tumor in 9% (Tables 4 and 5). The elapsed time from brain deaths is measured from diagnosis of clinical brain death to cardiac asystole (Fig. 2). All patients had final cardiac asystole while still being ventilated.(ABSTRACT TRUNCATED AT 250 WORDS)
沃克指出,脑死亡的发生率约占所有死亡人数的1%,因此脑死亡是一种常见状态。根据詹尼特等人的研究,脑死亡的发生现在是一个相对频繁的事件,在英国每年约有4000例。但从任何已发表的报告中都无法发现脑死亡的实际情况。在杏林大学医院过去的11年(1973 - 1983年)里,我们研究了121例根据日本标准被诊断为脑死亡的病例。日本标准要求病理为原发性严重脑损伤,因此我们没有关注继发脑损伤导致的脑死亡。我们分析了与脑死亡相关的因素,即年发病率、年龄、性别分布、初步诊断以及从脑死亡到心脏死亡的时间间隔。过去5年脑死亡发生率的上升可能是由于严重脑损伤患者数量的增加(表1)。在年龄分布方面,五十多岁患者数量较多可能分别反映了创伤性和血管性疾病的人类年龄倾向(图1和表2)。男性占主导这一事实与面临的脑外伤风险更高有关(表3)。初步诊断中,60%的病例为脑血管意外,尤其是41%为蛛网膜下腔出血,31%为头部损伤,9%为脑肿瘤(表4和表5)。从脑死亡到心脏死亡的时间间隔是从临床脑死亡诊断到心脏停搏来衡量的(图2)。所有患者在仍接受通气时最终出现心脏停搏。(摘要截选至250字)